Rafał Donczew

This study identifies the extra-terminal domain as essential for BET protein function in transcription and chromatin occupancy.

The paper maps DNA binding and regulatory targets for nearly all yeast transcription factors, revealing that TF binding does not always correlate with gene regulation and many TFs have dual functions.

The paper describes an end-to-end workflow combining AID system and SLAM-seq to study direct effects of transcriptional regulators in S. cerevisiae using BET proteins as a test case.

The paper investigates the genome-wide roles of yeast Mediator (MED) by depleting its activator-binding domain and finds that MED is directly recruited to most promoters independently of enhancers and activators.

This study investigates the role of Bdf1/2 in yeast transcription, finding they regulate both initiation and elongation, similar to human BET proteins.

The paper improves the ChEC-seq method to more accurately map transcription coactivators and transcription factors' genome-wide DNA binding sites.

The paper identifies two gene classes regulated by TFIID and SAGA in yeast, showing functional redundancy for some genes and distinct dependency for others.