Nathan A. Kimbrel

This study identifies shared and distinct genetic factors underlying suicidality phenotypes using GWAS and structural equation modelling.

The paper examines how polygenic risk for suicide attempts interacts with alcohol use disorder and childhood adversity to influence suicide attempt risk.

This study identifies a genetic link between externalizing traits and suicide risk using genomic data and electronic health records from over 500,000 veterans.

This study identifies correlates of risk for disinhibited behaviors in veterans using polygenic scores and electronic health records, finding strong associations with substance use disorders and related health outcomes.

This study relaxes GWAS significance thresholds and uses GRIN to identify additional genes linked to suicidal behavior, which replicate across cohorts and show stronger biological connections.

This study tests if functionally guided rTMS can modulate amygdala activation via its connectivity with the medial prefrontal cortex, finding increased activation post-rTMS.

This study examines how threat during goal pursuit affects amygdala-prefrontal cortex connectivity in PTSD, finding disrupted connectivity and altered vmPFC activation in PTSD patients compared to trauma-exposed controls.

This study identifies ten novel methylation loci associated with PTSD through a meta-analysis of 1,896 cases and controls across ten cohorts, highlighting the AHRR locus and its link to kynurenine levels.

This study conducts the largest GWAS for PTSD, identifying 6 genome-wide significant loci in European and African ancestries and highlighting novel biological pathways.