James Iain Provan

The paper measures the topological linkage change during Xer recombination at the psi site of plasmid pSC101, finding a +4 change consistent with a specific reaction mechanism.

The paper investigates the integration order of IMEXs in V. cholerae, showing that TLC{Phi} and VGJ{Phi} encode Xer activators that facilitate CTX{Phi} integration, explaining the observed integration order in pandemic lineages.

This paper introduces a high-throughput AFM-based pipeline using deep learning to trace DNA topology, revealing new insights into DNA structures and their interactions.

The paper characterizes genetic circuit components in E. coli to develop a biosensor for detecting Campylobacter jejuni using xylulose as a biomarker.