David J. Sherratt

RecA structure kinetics determine SOS dynamics and predict spontaneous cell death

The paper shows RecA* structure dynamics predict spontaneous cell death in E. coli by linking SOS response magnitude to DNA repair kinetics.

Change in topological linking number during Xer recombination at the plasmid pSC101 psi site

The paper measures the topological linkage change during Xer recombination at the psi site of plasmid pSC101, finding a +4 change consistent with a specific reaction mechanism.

Self-organised segregation of bacterial chromosomal origins

The paper proposes a self-organising model explaining how bacterial chromosomal origins are positioned and partitioned during the cell cycle, showing agreement with experimental data.

Pathways of DNA unlinking: A story of stepwise simplification

The paper analyzes minimal unlinking pathways of DNA replication links using computational methods and finds that the previously identified minimal pathway is the most probable.