ImmunologybioRxivPreprint
Acetoacetate suppresses colon cancer via an MR1-MAIT axis
Slater L. Clay, Geniver El Tekle, Edrees H. Rashan…·Wendy S. Garrett
This study shows that acetoacetate suppresses colon cancer by expanding and activating MAIT cells via the MR1 receptor, offering a potential immunotherapy approach.
DOI 10.1101/2025.10.29.685375