Author

Slater L. Clay

Harvard UniversityORCID 0000-0002-1966-892XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Diogo Fonseca‐PereiraiD· 2 shared Geniver El TekleiD· 2 shared Jon ClardyiD· 2 shared Jonathan N. GlickmaniD· 2 shared Monia Michaud· 2 shared Natalia Andreeva· 2 shared Sena Bae· 2 shared Sway P. CheniD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Diogo Fonseca‐PereiraORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Microbial-associated acylated putrescines as immunomodulatory molecules in inflammatory bowel diseases

Sena Bae, Julián Ávila-Pacheco, Slater L. Clay, Sunghee Bang, Milcah C. Scott, Natalia Andreeva, Monia Michaud, Diogo Fonseca‐Pereira, Eunyoung Chun, Y. Grace Cao, Yancong Zhang, Amrisha Bhosle, Rosa M. Perez, Gleb Pishchany, Hera C. Vlamakis, , Wendy S. Garrett

The paper identifies N-acyl putrescines, particularly NOP, as immunomodulatory metabolites produced by gut microbiota that suppress inflammation in IBD models.

bioRxiv · Aug 25, 2026 · PreprintImmunology

Acetoacetate suppresses colon cancer via an MR1-MAIT axis

Slater L. Clay, Geniver El Tekle, Edrees H. Rashan, Diogo Fonseca‐Pereira, Yern‐Hyerk Shin, Natalia Andreeva, Geicho Nakatsu, Ayesha F. Lobo, Sway P. Chen, Sena Bae, Monia Michaud, Jonathan N. Glickman, Jon Clardy, Matthew G. Vander Heiden, Wendy S. Garrett

This study shows that acetoacetate suppresses colon cancer by expanding and activating MAIT cells via the MR1 receptor, offering a potential immunotherapy approach.

bioRxiv · Oct 29, 2025 · PreprintImmunology