NFATc3 enhances DREAM complex-driven tumorigenesis
Jieun Ahn, Yoojeong Seo, Jinho Jang…·Jae‐Il Park
This study identifies NFATc3's role in promoting DREAM complex-driven tumorigenesis in lung adenocarcinoma by enhancing target gene transactivation.
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The University of Texas MD Anderson Cancer CenterORCID 0000-0001-7243-5386Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Jieun Ahn, Yoojeong Seo, Jinho Jang…·Jae‐Il Park
This study identifies NFATc3's role in promoting DREAM complex-driven tumorigenesis in lung adenocarcinoma by enhancing target gene transactivation.
Jinho Jang, Yoojeong Seo, Kyung-Pil Ko…·Jae‐Il Park
This study compares immune and stromal differences between orthotopic and subcutaneous gastric tumors using scRNA-seq, finding distinct TME features in each model.
Yoojeong Seo, Jinho Jang, Kyung-Pil Ko…·Jae‐Il Park
This study shows that CRACD inactivation in gastric cancer leads to immune evasion via oxidative stress-activated PD-L1, suggesting HIF1 and PD-L1 as therapeutic targets.