Author

Hengchen Liu

Howard Hughes Medical InstituteORCID 0000-0001-7263-6735Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew G. DilliniD· 1 shared Audrey Evangelista· 1 shared C. Kimberly TsuiiD· 1 shared Ellen A. RobeyiD· 1 shared Esther Jeong Yoon KimiD· 1 shared Hanlin ZhangiD· 1 shared Jesse Garcia CastilloiD· 1 shared Lara K. MahaliD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Andrew G. DillinORCID

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1 paper

Recent·Most cited

Age-related remodeling of the glycocalyx drives T cell exhaustion

Hanlin Zhang, C. Kimberly Tsui, Jesse Garcia Castillo, Esther Jeong Yoon Kim, Audrey Evangelista, Hengchen Liu, Larry K. Joe, Nicholas M. Twells, Ellen A. Robey, Lara K. Mahal, Michel J.P. DuPage, Andrew G. Dillin

This study shows that aging reduces 2,6-linked sialic acids on T cells, leading to exhaustion and impaired immune function.

Science Advances · Sep 26, 2025Peer-reviewedImmunology