BiochemistryJournal of the American Chemical SocietyPeer-reviewed
Structural insights into inhibitor mechanisms on immature HIV-1 Gag lattice revealed by high-resolution in situ single-particle cryo-EM
Chunxiang Wu, Megan E. Meuser, Juan S. Rey…·Yong Xiong
This study determines high-resolution structures of immature HIV-1 particles with inhibitors BVM and LEN bound using cryo-EM, revealing their distinct binding mechanisms and effects on Gag lattice architecture.