BiophysicsScience AdvancesPeer-reviewed
Afadin mediates cadherin-catenin complex clustering on F-actin linked to cooperative binding and filament curvature
Rui Gong, Matthew J. Reynolds, Xiaoyu Sun, Gregory M. Alushin
This study shows afadin and vinculin enhance cadherin-catenin complex binding to F-actin, stabilizing it through cooperative interactions and promoting filament curvature.
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