Author

Pilar Negredo

Universidad Autónoma de MadridORCID 0000-0001-7274-5579Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Juan Antonio BernaliD· 2 shared Manuela García LópeziD· 2 shared Alberto RábanoiD· 1 shared Ana Isabel CasasiD· 1 shared Ana María CuervoiD· 1 shared Ángel NúñeziD· 1 shared César PorreroiD· 1 shared Cristina Fernández‐MendíviliD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

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10 top collaborators · 38 mutual co-author links

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2 shared papersNeuroscience

Juan Antonio BernalORCID

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2 papers

Recent·Most cited

NeuroscienceBrain Behavior and ImmunityPeer-reviewedJan 4, 2026

Long-term Nrf2-driven microglial repopulation mitigates microgliosis, neuronal loss and cognitive deficits in tauopathy

Lucía Viqueira, Elisa Navarro, Pilar Negredo…·Manuela García López

This study shows that combining Nrf2 activation with microglial repopulation after PLX5622 treatment improves cognitive deficits, neuronal loss, and mitochondrial function in a tauopathy model.

2 citations

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 14, 2020

Neuronal NOX4 knockdown alleviates pathological tau-related alterations in a humanized mouse model of tauopathy

Enrique Luengo, Paula Trigo-Alonso, Cristina Fernández‐Mendívil…·Manuela G. López

This study shows that reducing NOX4 in neurons alleviates tau-related pathology and cognitive decline in a mouse model of tauopathy.

DOI 10.1101/2020.10.14.338954

mouseexperimental assay

𝕏 PostBluesky