Frank C. Ko

The paper identifies A{delta}-HTMRs as fast-conducting mechanonociceptors that drive protective pain responses through unique spinal reflex circuits.

This study shows that repeated NGF injections into mouse knees cause multiple OA-like features without cartilage damage.

This study identifies sensory fiber types in mouse TMJ tissues using immunohistochemistry, finding peptidergic fibers dominate with minimal non-peptidergic nociceptors.

This study shows that acute systemic macrophage depletion reduces pain-related behaviors in osteoarthritic mice without affecting joint damage.

This paper develops a 3D imaging workflow using clearing-enabled light sheet microscopy to map mouse knee joint innervation and demonstrates changes in nerve density after NGF injection.