Spencer Fullam

Fast-conducting mechanonociceptors uniquely engage reflexive and affective pain circuitry to drive protective responses

The paper identifies A{delta}-HTMRs as fast-conducting mechanonociceptors that drive protective pain responses through unique spinal reflex circuits.

A standardized, open-source, portable model for noninvasive joint injury in mice

The paper introduces a standardized, open-source protocol for noninvasive joint injury in mice, resulting in post-traumatic osteoarthritis, and provides tools for reproducibility and analysis.

Identification of Sensory Fiber Types in Mouse Temporomandibular Joint Tissues

This study identifies sensory fiber types in mouse TMJ tissues using immunohistochemistry, finding peptidergic fibers dominate with minimal non-peptidergic nociceptors.

Clearing-enabled light sheet microscopy as a novel method for three-dimensional mapping of the sensory innervation of the mouse knee

This paper develops a 3D imaging workflow using clearing-enabled light sheet microscopy to map mouse knee joint innervation and demonstrates changes in nerve density after NGF injection.

Reduced Capsaicin-Induced Mechanical Allodynia and Neuronal Responses in the DRG in the Presence of Shp1 Overexpression

This study shows that SHP-1 overexpression reduces capsaicin-induced mechanical allodynia in both male and female mice by dephosphorylating TRPV1 in DRG neurons.