Ceres Fernández–Rozadilla

This study identifies rs3087967 as the causal variant at 11q23.1 that increases colorectal cancer risk by dysregulating POU2AF2, a key activator of tuft cell transcription.

This study improves polygenic risk scores for colorectal cancer by combining Asian and European ancestry data, enhancing risk prediction across diverse racial and ethnic groups.

The paper analyzes genome-wide data from Spanish individuals to reveal fine-scale genetic structure and historical population movements, including North African ancestry from the Muslim period.