Clare Bycroft

AlphaGenome Atlas: in silico mutagenesis of the entire human genome improves prioritization and interpretation of non-coding variants

AlphaGenome Atlas predicts regulatory effects of non-coding variants across the human genome, improving their prioritization and interpretation.

AlphaGenome: advancing regulatory variant effect prediction with a unified DNA sequence model

AlphaGenome predicts functional genomic measurements from DNA sequences with high resolution and accuracy across multiple modalities, outperforming existing methods in variant effect prediction.

Population structure of modern-day Italians reveals patterns of ancient and archaic ancestries in Southern Europe

The paper analyzes the genetic structure of modern-day Italians to reveal ancient and archaic ancestries shaping Southern European populations and Neanderthal DNA distribution.

Patterns of genetic differentiation and the footprints of historical migrations in the Iberian Peninsula

The paper analyzes genome-wide data from Spanish individuals to reveal fine-scale genetic structure and historical population movements, including North African ancestry from the Muslim period.

Genome-wide genetic data on ~500,000 UK Biobank participants

Quality-controlled genotypes for 488,377 UK Biobank participants at 805,426 markers, imputed to ~96 million variants, plus ancestry PCs, kinship (30.3% have close relatives enrolled) and HLA calls.