GAPDH is tethered to axonal transport vesicles by S-acylation
Nisandi N Herath, Jordan A. Kogut, Andrey A. Petropavlovskiy, Amelia H Doerksen, Charlotte A. Townsend, Anthony Dang, Gareth M. Thomas, Dale D. O. Martin, Shaun S. Sanders
The paper identifies S-acylation of GAPDH on cysteine 247 by ZDHHC5 and ZDHHC17 as essential for its association with axonal transport vesicles.
bioRxiv · Sep 21, 2026 · PreprintNeuroscience