Sarah Adams Schoenrock

This study identifies a shared genetic regulator linking metabolism and addiction-related behavior in mice and humans through a common enhancer regulating Eed/Me3 and EED/ME3.

The paper identifies genetic loci affecting cocaine sensitivity in Collaborative Cross mouse strains through QTL mapping and proposes candidate genes for further study.

The paper updates the MiniMUGA genotyping array's bioinformatic pipeline to enhance genetic QC in laboratory mice by improving marker annotation, consensus genotypes, and report usability.

The paper measures cocaine-induced behavioral sensitization across genetically diverse Collaborative Cross strains and their founders, identifying significant heritability and phenotypic variation.

The paper assesses cocaine-induced locomotor activation in 20 inbred mouse substrains from six lineages, identifying significant phenotypic differences that could inform genetic studies of addiction.

The paper uses Bayesian modeling to analyze XCI skew in genetically diverse mice, identifying a novel Xce allele linked to copy number changes.

The paper introduces MiniMUGA, a genotyping array for mouse genetic QC, showing it effectively discriminates strains, detects genetic constructs, and identifies sex chromosome abnormalities.

This study shows that including genetic and sex differences in mice improves the alignment of addiction-related traits with human studies.

The paper investigates parent-of-origin effects and environment-by-POE on behavior and gene expression using reciprocal F1 hybrids of inbred mouse strains exposed to different diets.