Lisa M. Tarantino

This study identifies a shared genetic regulator linking metabolism and addiction-related behavior in mice and humans through a common enhancer regulating Eed/Me3 and EED/ME3.

The paper identifies genetic loci affecting cocaine sensitivity in Collaborative Cross mouse strains through QTL mapping and proposes candidate genes for further study.

The paper examines behavioral variation in cocaine self-administration across multiple phases in genetically diverse mouse populations, identifying strain and sex differences and extreme strains for drug intake traits.

The paper updates the MiniMUGA genotyping array's bioinformatic pipeline to enhance genetic QC in laboratory mice by improving marker annotation, consensus genotypes, and report usability.

This study examines how different morphine withdrawal paradigms affect sleep behavior in male and female mice, finding sex-specific differences and highlighting the 3-day precipitated withdrawal model as most impactful.

The paper measures cocaine-induced behavioral sensitization across genetically diverse Collaborative Cross strains and their founders, identifying significant heritability and phenotypic variation.

The paper identifies genetic loci associated with reversal learning phenotypes in Diversity Outbred mice, revealing a genome-wide significant QTL on chromosome 7.

The paper assesses cocaine-induced locomotor activation in 20 inbred mouse substrains from six lineages, identifying significant phenotypic differences that could inform genetic studies of addiction.

The paper examines heritability of reward sensitivity and impulsivity traits in inbred mice and finds these traits are independent and heritable.

The paper uses Bayesian modeling to analyze XCI skew in genetically diverse mice, identifying a novel Xce allele linked to copy number changes.

The paper introduces MiniMUGA, a genotyping array for mouse genetic QC, showing it effectively discriminates strains, detects genetic constructs, and identifies sex chromosome abnormalities.

This study shows that including genetic and sex differences in mice improves the alignment of addiction-related traits with human studies.

This paper introduces mean-variance QTL mapping to identify novel QTL for circadian activity and exploratory behavior in mice, showing its superiority over traditional interval mapping in detecting both mean- and variance-controlling QTL.

The paper investigates parent-of-origin effects and environment-by-POE on behavior and gene expression using reciprocal F1 hybrids of inbred mouse strains exposed to different diets.