BiochemistryStructurePeer-reviewed
Structural Basis for Substrate Binding, Catalysis and Inhibition of Breast Cancer Target Mitochondrial Creatine Kinase by Covalent Inhibitor via Cryo-EM
Merve Demir, Laura Koepping, Ya Li…·Eduard A. Sergienko
The paper investigates the structural and mechanistic features of mitochondrial creatine kinase (uMtCK) and evaluates the efficacy of a covalent inhibitor in breast cancer cells.
3 citations