Taro Hitosugi

The paper identifies an uncompetitive allosteric inhibitor of mitochondrial creatine kinase that stabilizes loop closure, preventing creatine binding and phosphocreatine release.

This study identifies lysosomal lipid metabolism as a driver of pancreatic cancer cell invasion through local energy production and membrane remodeling.

This study compares proteomic and acylproteomic changes in two cell types after SDH loss, finding distinct adaptations that may explain tissue-specific tumorigenesis.

This study shows that CPT2-mediated fatty acid oxidation is not essential for humoral immunity in mice, as CPT2 deficiency does not impair B cell development, activation, or antibody production.

The paper investigates the structural and mechanistic features of mitochondrial creatine kinase (uMtCK) and evaluates the efficacy of a covalent inhibitor in breast cancer cells.