Samuel Shields

This study shows oxidative stress causes axonal atrophy by altering microtubules and EB1 function, and suggests targeting EB1 could prevent age-related neuronal decline.

This study identifies microtubule decay as a key driver of neuronal ageing in Drosophila and shows that enhancing microtubule networks can slow age-related decline.

The paper curates a database of senescence-associated genes and performs systems biology analyses to identify novel regulators and pathways of cellular senescence.