Natalia Sánchez‐Soriano

This study shows that declining autophagy in aged neurons leads to microtubule alterations, causing axonal and synaptic decay, and that enhancing autophagy can reverse these effects.

The paper identifies microtubule-curling as a marker of axonal atrophy by analyzing gene deficiencies in Drosophila neurons, revealing two distinct mechanisms linked to neurodegeneration.

This study shows oxidative stress causes axonal atrophy by altering microtubules and EB1 function, and suggests targeting EB1 could prevent age-related neuronal decline.

This study identifies microtubule decay as a key driver of neuronal ageing in Drosophila and shows that enhancing microtubule networks can slow age-related decline.

This study investigates the role of spectraplkin proteins in axon growth and maintenance, revealing that their function depends on a balanced interaction with F-actin and that they have actin-independent roles in microtubule bundling.