Author

Miguel Jociles-Ortega

Universidad Rey Juan CarlosORCID 0000-0001-7393-9818Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Ana Chocarro‐CalvoiD· 2 shared Ana Ramírez-SáncheziD· 2 shared Colin R. GodingiD· 2 shared Custodia García‐JiméneziD· 2 shared José Manuel García-MartíneziD· 2 shared Pakavarin LouphrasitthipholiD· 2 shared Carmen FiuzaiD· 1 shared Irene Torrens-MartíneziD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

Ana Chocarro‐CalvoORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 7, 2025

Metabolic buffering suppresses phenotype switching in cancer

Ana Ramírez-Sánchez, Miguel Jociles-Ortega, José Manuel García-Martínez…·Ana Chocarro‐Calvo

This study shows that glycogen storage and metabolic buffering suppress phenotype switching in melanoma, with low glycogen levels linked to invasion and poor survival.

DOI 10.1101/2025.04.07.647576

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintJan 21, 2024

Phenotype-specific melanoma uptake of fatty acid from human adipocytes activates AXL and CAV1-dependent beta-catenin nuclear accumulation

Ana Chocarro‐Calvo, Miguel Jociles-Ortega, José Manuel García-Martínez…·Colin R. Goding

The paper shows that MITFLow melanoma cells uptake fatty acids from adipocytes, activating AXL and CAV1 to drive beta-catenin nuclear accumulation, promoting invasion.

3 citations

humanproteomics

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