Author

Margaret Lise Gardel

University of ChicagoORCID 0000-0003-1846-9854Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Developmental Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Shailaja SeetharamaniD· 2 shared Alex M. PlumiD· 1 shared Allison M. Lynch· 1 shared Amanda Brooke JohnsoniD· 1 shared Anjon AudhyaiD· 1 shared Bethany G. LucasiD· 1 shared Emma J. van BodegraveniD· 1 shared Ha Ram KimiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersDevelopmental Biology

Shailaja SeetharamanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintOct 20, 2026

APLNR regulates directed migration to spatially pattern mesoderm in human gastruloids

Amanda Brooke Johnson, Shailaja Seetharaman, LiAng Yao…·Margaret Lise Gardel

This study identifies APLNR as a regulator of directed mesoderm migration in human gastruloids, showing chemotactic guidance through an epithelial ligand field.

DOI 10.64898/2026.10.19.760207

humanspatial transcriptomics

𝕏 PostBluesky

Cell BiologyThe EMBO JournalPeer-reviewedMay 26, 2026

Mechanosensitive FHL2 tunes endothelial function

Shailaja Seetharaman, John Michael Devany, Ha Ram Kim…·Margaret L. Gardel

This study identifies FHL2 as a mechanosensitive protein that drives endothelial dysfunction under athero-prone flow conditions by modulating adherens junctions and Rho-ROCK signaling.

5 citations

humanbulk RNA-seq

𝕏 PostBluesky

Developmental BiologybioRxivPreprintSep 30, 2021

TES-1/Tes protects junctional actin networks under tension from self-injury during epidermal morphogenesis in the C. elegans embryo

Allison M. Lynch, Bethany G. Lucas, Jonathan D. Winkelman…·Jeff D. Hardin

This study identifies TES-1 as a protein that stabilizes junctional actin networks during cell shape changes in C. elegans embryos by preventing self-injury under tension.

DOI 10.1101/2021.09.30.462556

C. elegansexperimental assay

𝕏 PostBluesky