Author

George P. Brownrigg

University of British ColumbiaORCID 0000-0001-7412-5381Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1

Frequent Co-Authors

James D. JohnsoniD· 2 shared Jason C. RogalskiiD· 2 shared Bhavya Sabbineni· 1 shared Chieh Min Jamie ChuiD· 1 shared Haoning Howard CeniD· 1 shared Jelena KoliciD· 1 shared Leonard J. FosteriD· 1 shared Renata MoravcovaiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

James D. JohnsonORCID

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2 papers

Recent·Most cited

Cell BiologyiSciencePeer-reviewedFeb 17, 2025

Signal transduction pathways controlling Ins2 gene activity and β cell state transitions

Chieh Min Jamie Chu, Bhavya Sabbineni, Haoning Howard Cen…·James D. Johnson

The paper identifies Ins2 gene activity states in beta cells and shows that cAMP activators drive transitions between these states.

3 citations

mouseproteomics

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Cell BiologyEndocrinologyPeer-reviewedJun 28, 2024

β-Hydroxybutyrate promotes basal insulin secretion while decreasing glucagon secretion in mouse and human islets.

Risha Banerjee, Ying Guo Zhu, George P. Brownrigg…·Jelena Kolic

This study shows that β-hydroxybutyrate (βHB) increases insulin secretion and decreases glucagon secretion in human and mouse islets at physiological glucose concentrations.

18 citationstop 4%

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