Bryce E. Nickels

The paper reports structures of long-range coupled transcription-translation complexes (TTC-LC) in E. coli, showing how they differ from TTC-B and their roles in transcription-translation coupling.

The paper investigates how the TFIIH-Pol II-TFIIE interface influences promoter scanning and TSS selection in yeast by analyzing genetic mutants and TSS sequencing data.

The paper quantitatively analyzes TSS selection in yeast using a new assay, showing sequence, Pol II activity, and NTP levels influence initiation efficiency.

This paper reports atomic structures of Qλ, showing it forms a nozzle to prevent RNA hairpin formation, unlike Q21, and uses a different mechanism and loading process involving NusA.

This study investigates reiterative transcription initiation, showing RNA extension occurs without DNA scrunching, involves a short RNA-DNA hybrid, and uses an alternative RNA exit pathway.

This study investigates how Ssl2/TFIIH influences transcription start site scanning by RNA Polymerase II in yeast, identifying alleles that alter TSS selection and scanning processivity.

The paper investigates promoter scanning by Pol II in yeast, showing that it occurs across all promoters and is influenced by Pol II activity and promoter architecture.

This study identifies the mechanism of transcription start site (TSS) selection by bacterial RNA polymerase (RNAP) through experimental assays showing DNA scrunching and antiscrunching.