Author

Jacob Stewart-Ornstein

University of PittsburghORCID 0000-0001-8255-5904Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Andrew H. NgiD· 1 shared Antonina HafneriD· 1 shared Ariana C. DetwileriD· 1 shared Bennett Van HouteniD· 1 shared Galit LahaviD· 1 shared Hana El‐SamadiD· 1 shared Lauren T. Neves· 1 shared Lindsey C. Osimiri· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperSystems Biology

Andrew H. NgORCID

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3 papers

Recent·Most cited

Molecular BiologyNature Structural & Molecular BiologyPeer-reviewedJun 30, 2022

Telomeric 8-oxoguanine drives rapid premature senescence in the absence of telomere shortening

Ryan P. Barnes, Mariarosaria De Rosa, Sanjana A. Thosar…·Patricia Lynn Opresko

This study shows that telomeric 8-oxoguanine induces premature senescence without telomere shortening by causing replication stress and dysfunction.

128 citationstop 1%

humanDNA methylation

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Systems BiologyCell SystemsPeer-reviewedSep 7, 2020

Optogenetic control reveals differential promoter interpretation of transcription factor nuclear translocation dynamics

Susan Y. Chen, Lindsey C. Osimiri, Michael W. Chevalier…·Hana El‐Samad

The paper introduces CLASP, an optogenetic tool to control TF localization, and shows differential promoter responses to pulsatile vs. continuous TF inputs.

64 citations

experimental assay

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GenomicsBMC Molecular and Cell BiologyPeer-reviewedFeb 18, 2020

Identification of universal and cell type specific p53 DNA binding

Antonina Hafner, Lyubov Kublo, Michael Tsabar…·Jacob Stewart-Ornstein

The paper identifies universal and cell type specific p53 DNA binding sites by analyzing 12 epithelial cell lines after ionizing radiation.

25 citations

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