Author

David A. Boothman

Indiana University Melvin and Bren Simon Comprehensive Cancer CenterORCID 0000-0001-7474-9020Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Amber L. MosleyiD· 1 shared Aruna B. WijeratneiD· 1 shared Avery M. RunnebohmiD· 1 shared Cristina M. FurduiiD· 1 shared Edward A. MoteaiD· 1 shared Gitanjali RoyiD· 1 shared H. R. Sagara WijeratneiD· 1 shared Jarrett J. Smith· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Amber L. MosleyORCID

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2 papers

Recent·Most cited

Cancer BiologyJournal of Proteome ResearchPeer-reviewedNov 6, 2026

Unraveling Systemic Responses to NQO1-Activated IB-DNQand Rucaparib Single and Dual Agent Therapy in Triple-Negative Breast Cancers

Avery M. Runnebohm, H. R. Sagara Wijeratne, Sarah A. Peck Justice…·Amber L. Mosley

This study evaluates the effects of IB-DNQ and Rucaparib on TNBC cells, revealing synergistic effects and novel protein biophysical changes via thermal proteome profiling.

DOI 10.1021/acs.jproteome.6c00632

humanproteomics

𝕏 PostBluesky

Systems BiologyCell SystemsPeer-reviewedJan 1, 2021

Personalized Genome-Scale Metabolic Models Identify Targets of Redox Metabolism in Radiation-Resistant Tumors

Joshua E. Lewis, Tom E. Forshaw, David A. Boothman…·Melissa Lambeth Kemp

The paper develops a bioinformatics pipeline to integrate multi-omics data into personalized genome-scale metabolic models, identifying redox metabolism targets in radiation-resistant tumors.

61 citationstop 3%

humanwhole-genome sequencing

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