Author

Michael C. Jensen

Seattle Children's Research InstituteORCID 0000-0001-7477-3063Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Ryma Toumi· 2 shared Shannon K. OdaiD· 2 shared Aalton M LandeiD· 1 shared Andrea TimpanaroiD· 1 shared Anja KordowskiiD· 1 shared Ardizon ValdeziD· 1 shared Ashmitha RajendraniD· 1 shared Benjamin C. CurtisiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

Ryma Toumi

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Genome-wide CRISPRa screens nominate modulators of CAR T cell survival within distinct tumor cytokine milieus

Benjamin C. Curtis, Cailyn H. Spurrell, Lindsay Flint, Aalton M Lande, Marissa Leonardi, James M. Rosser, Tavie Parker, Tiffanie Chai, Ardizon Valdez, Ryma Toumi, Nat Murren, Michael Fitzgerald, Jasmin Martinez-Reyes, Finn Watt, Chris Saxby, , Shannon K. Oda

This paper develops a CRISPRa-based method to identify genes enhancing CAR T cell survival in different tumor environments.

Molecular Therapy — Nucleic Acids · Sep 29, 2026Peer-reviewedImmunology

Preclinical efficacy of combinatorial B7-H3 CAR T cells and ONC206 against diffuse intrinsic pontine glioma

Andrea Timpanaro, Edward Z. Song, Ryma Toumi, Leonel Elena-Sanchez, Caroline Piccand, Kelsey Marie Nemec, Anja Kordowski, Davina Lau, Scott Johnson, Lily I. Winter, Ashmitha Rajendran, Rebecca J. Ronsley, Shannon K. Oda, Joshua A. Gustafson, Jason Wendler, , Nicholas Alexander Vitanza

This paper evaluates the combination of B7-H3 CAR T cells and ONC206 against DIPG models, showing enhanced anti-tumor efficacy in vitro and in vivo.

Neuro-Oncology · Jan 30, 2026Peer-reviewedCancer Biology