Ashmitha Rajendran

The paper analyzes bulk RNA-seq data from brain tumors and healthy samples to identify differential regulation of synaptic components and their impact on tumor progression and patient survival.

This study investigates how SARS-CoV-2 S1 protein induces systemic immune responses and long-term anxiety-like behaviors in mice.

This paper evaluates the combination of B7-H3 CAR T cells and ONC206 against DIPG models, showing enhanced anti-tumor efficacy in vitro and in vivo.

This paper uses topic modeling to identify developmental states in medulloblastoma subtypes across multiple datasets and technologies.

This study identifies CTPS1 as a vulnerability in MYC-driven medulloblastoma and shows that combining CTPS1 and CHK1 inhibition synergistically reduces tumor growth in vivo.