GeneticsbioRxivPreprint
A Promoter Competition Hub Orchestrates Runx1 Alternative Promoter Usage during Skeletal Muscle Stem Cell Activation
DOI 10.64898/2026.07.13.738242
Author
Liangqiang He
Chinese University of Hong KongORCID 0000-0001-7480-7665Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2020-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 33 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship6 papers
Recent·Most cited
- GeneticsMolecular TherapyPeer-reviewed
In vivo systematic detection of the outcomes of CRISPR/Cas9 mediated DNA repair in skeletal muscle stem cells
Liangqiang He, Yang Fu, Ziliu Wang…·Huating Wang
This study systematically profiles CRISPR/Cas9 repair outcomes in skeletal muscle stem cells, revealing both expected and novel large on-target modifications and their regulation by repair pathways.
3 citationstop 3% - Molecular BiologyGenome biologyPeer-reviewed
DNA G-quadruplex Profiling Reveals Functional and Mechanistic Role of G-quadruplexes in Skeletal Muscle Stem Cells
Xiaona Chen, Feng Yang, Suyang Zhang…·Huating Wang
This study maps G-quadruplexes in skeletal muscle stem cells and shows their role in promoting activation and regeneration through chromatin looping and transcription factor binding.
4 citations - Molecular BiologyeLifePeer-reviewed
Nuclear m6A Reader YTHDC1 Promotes Muscle Stem Cell Activation/Proliferation by Regulating mRNA Splicing and Nuclear Export
Yulong Qiao, Qiang Sun, Xiaona Chen…·Huating Wang
This study identifies YTHDC1 as a critical regulator of muscle stem cell activation and proliferation by modulating mRNA splicing and nuclear export during regeneration.
81 citationstop 1% - Developmental BiologybioRxivPreprint
seRNA PAM-1 regulates skeletal muscle satellite cell activation and aging through trans regulation of Timp2 expression synergistically with Ddx5
Karl Kam Hei So, Yile Huang, Suyang Zhang…·Huating Wang
This study identifies PAM-1, a long non-coding RNA that regulates skeletal muscle satellite cell activation and aging by trans-regulating Timp2 expression with Ddx5.
DOI 10.1101/2021.10.06.463443 - GeneticsbioRxivPreprint
In Vivo Study of Key Transcription Factors in Muscle Satellite Cells by CRISPR/Cas9/AAV9-sgRNA Mediated Genome Editing
Liangqiang He, Yingzhe Ding, Yu Fen Zhao…·Huating Wang
This study develops a CRISPR/Cas9/AAV9-sgRNA system for in vivo genome editing in muscle satellite cells to investigate key transcription factors during activation and regeneration.
3 citations