Author

Dieter Lütjohann

University Hospital BonnORCID 0000-0002-7941-8308Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Anja KerksiekiD· 2 shared Aaron Ernesto Marure-RojanoiD· 1 shared Aleksandar Arsović· 1 shared Antonio Vázquez Cobá· 1 shared Clara S Berger· 1 shared Claudia DöringiD· 1 shared Frédérique RenéiD· 1 shared Georg W. J. AuburgeriD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Anja KerksiekORCID

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2 papers

Recent·Most cited

Reducing CETP activity prevents memory decline in an Alzheimer's disease mouse model

Jasmine Phénix, Isabel MacKenzie Sarty, Megan S. Katz, Antonio Vázquez Cobá, Aaron Ernesto Marure-Rojano, Hannah Nie, Anja Kerksiek, Indie Jerry, Clara S Berger, Robert S. Kiss, Dieter Lütjohann, William A. Pastor, Judes Poirier, Lisa Marie Munter

The paper shows that reducing CETP activity in Alzheimer's disease mice prevents memory decline and alters lipid and gene expression profiles, supporting CETP as a therapeutic target.

EMBO Molecular Medicine · Aug 3, 2026Peer-reviewedNeuroscience

Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression

Júlia Canet-Pons, Nesli-Ece Şen, Aleksandar Arsović, Luis Enrique Almaguer-Mederos, Melanie Vanessa Halbach, Jana Key, Claudia Döring, Anja Kerksiek, Gina Picchiarelli, Raphaelle Cassel, Frédérique René, Stéphane Dieterle, Nina V. Fuchs, Renate König, Luc Dupuis, , Georg W. J. Auburger

This study examines an SCA2 mouse model to identify molecular mechanisms of spinal cord pathology, finding progressive TDP43 aggregation and cholesterol biosynthesis suppression.

Neurobiology of Disease · Feb 10, 2021Peer-reviewedNeuroscience