Author

Florian Morati

Centre National de la Recherche ScientifiqueORCID 0000-0001-7512-9501Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 1 Organism:multiple species· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Mauro ModestiiD· 2 shared Anusha Budida· 1 shared Atharv S. GarjeiD· 1 shared Brett TayloriD· 1 shared David CorteziD· 1 shared Elin Persson· 1 shared Emilie C. B. Desclos· 1 shared Evgeniya PavlovaiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersMolecular Biology

Mauro ModestiORCID

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintDec 17, 2025

It takes two (Ku) to repair: Mechanistic insights into the minimal NHEJ system of Mycobacterium Tuberculosis

Florian Morati, Evgeniya Pavlova, Anusha Budida…·Fredrik Westerlund

This study investigates the minimal NHEJ system in M. tuberculosis using structural simulations, assays, and single-molecule analysis, revealing Ku-LigD interactions and their impact on enzymatic activity.

DOI 10.64898/2025.12.16.694593

multiple speciesstructural biology

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Molecular BiologyJournal of Molecular BiologyPeer-reviewedOct 1, 2023

CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity

Madison B. Adolph, Atharv S. Garje, Swati Balakrishnan…·David Cortez

The paper identifies RADX separation of function mutants using CRISPR base editing screens, showing reduced RAD51 ATP hydrolysis activity and replication defects.

4 citations

experimental assay

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Molecular BiologyNature CommunicationsPeer-reviewedJul 12, 2021

Distinct pathways of homologous recombination controlled by the SWS1-SWSAP1-SPIDR complex

Rohit Prakash, Thomas Sandoval, Florian Morati…·Maria Jasin

This study identifies the SWS1-SWSAP1-SPIDR complex as a regulator of distinct homologous recombination pathways, with specific roles in inter-homolog HDR and cancer-related genomic instability.

50 citations

mouseexperimental assay

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