Shukti Chakravarti

This study shows that ECM proteoglycans lumican and biglycan enhance antiviral immunity in HSV-1 corneal infections by promoting immune cell recruitment and cytokine production.

This study identifies increased MDA and GPX3 in KC tears and NRF2 dysfunction in stromal cells, suggesting potential biomarkers and therapeutic targets for keratoconus.

This study shows that lumican and biglycan, ECM proteoglycans, protect against allergic contact dermatitis by limiting proinflammatory CD4+ T cells through paracrine regulation.

This study identifies Treg cells and IFN-γ-producing Th1 cells as key drivers of Sjögren's Syndrome pathogenesis using a mouse model and single-cell transcriptomics.

This study uses single-cell RNA-seq to map cell fates in human cornea organoids and identifies developmental states of corneal cell types.