Author

Amanda R. Jiang

Boston Children's HospitalORCID 0000-0001-7545-2667Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Donald E. IngberiD· 2 shared Yuncheng ManiD· 2 shared Aakanksha GulatiiD· 1 shared Aliçan ÖzkaniD· 1 shared Anna M. Howley· 1 shared Bogdan BudnikiD· 1 shared Chaitra BelguriD· 1 shared Christos KyprianouiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMolecular Biology

Donald E. IngberORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintNov 5, 2025

Endothelial CLK2 as a therapeutic target for acute radiation syndrome

Ryan R. Posey, Aliçan Özkan, Yuncheng Man…·Donald E. Ingber

This study identifies CLK2 as a therapeutic target for acute radiation syndrome by showing CLK2 inhibitors protect endothelial cells and reverse radiation injury in human organ models.

DOI 10.1101/2025.11.05.686891

humanproteomics

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BioengineeringbioRxivPreprintAug 13, 2024

Exacerbation of influenza virus induced lung injury by alveolar macrophages and its suppression by pyroptosis blockade in a human lung alveolus chip

Yuncheng Man, Yunhao Zhai, Amanda R. Jiang…·Donald E. Ingber

This study shows that alveolar macrophages worsen influenza-induced lung injury in a human lung alveolus chip, but blocking pyroptosis reduces inflammation and tissue damage.

7 citations

humanspatial transcriptomics

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