Yuncheng Man

This study shows that lung-targeted delivery of immunostimulatory dsRNA via LNPs enhances systemic cytokine responses and antitumor activity in melanoma models.

Endolysin BNT331 combined with Lactobacillus crispatus reduces bacterial load and suppresses inflammation in a human vagina chip model of bacterial vaginosis.

This study identifies CLK2 as a therapeutic target for acute radiation syndrome by showing CLK2 inhibitors protect endothelial cells and reverse radiation injury in human organ models.

This paper develops a human lymphoid follicle chip platform to model intramuscular mRNA vaccine responses, showing it can replicate immune responses to both naive and recall antigens.

This study shows that alveolar macrophages worsen influenza-induced lung injury in a human lung alveolus chip, but blocking pyroptosis reduces inflammation and tissue damage.