Author

Daniel G. Gibson

J. Craig Venter Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Synthetic Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

Ben E. BlackiD· 2 shared Gabriel J. BirchakiD· 2 shared John I. GlassiD· 2 shared Prakriti KashyapiD· 2 shared Praveen Kumar AlluiD· 2 shared Adam J. RiesselmaniD· 1 shared Connor A. HortoniD· 1 shared David Lips· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersSynthetic Biology

Ben E. BlackORCID

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3 papers

Recent·Most cited

Protein-only centromeric chromatin assembly streamlines human artificial chromosome formation

Gabriel J. Birchak, Praveen Kumar Allu, Prakriti Kashyap, Guhan Kaliyaperumal Anbalagan, Shu-Cheng Chuang, Glennis A. Logsdon, Daniel G. Gibson, John I. Glass, Ben E. Black

This paper describes the creation of a 2 Mb human artificial chromosome (HAC) using a protein-only centromere seeding approach that bypasses genetic engineering of target cells.

bioRxiv · Jan 29, 2026 · PreprintSynthetic Biology

Rapid assembly of functional modules for generating human artificial chromosome constructs compatible with epigenetic centromere seeding

Gabriel J. Birchak, Daniel G. Gibson, Praveen Kumar Allu, Prakriti Kashyap, John I. Glass, Ben E. Black

This paper describes a method to rapidly assemble functional modules for human artificial chromosomes (HACs) that can be seeded with epigenetic centromere components.

Chromosome Research · Dec 1, 2025Peer-reviewedSynthetic Biology

Rapid genome recoding by iterative recombineering of synthetic DNA

Yu Heng Lau, Finn Stirling, James Kuo, Michiel A. P. Karrenbelt, Yujia A. Chan, Adam J. Riesselman, Connor A. Horton, Elena Schäfer, David Lips, Matthew T. Weinstock, Daniel G. Gibson, Jeffrey C. Way, Pamela A. Silver

This paper introduces a method for rapid genome recoding in Salmonella typhimurium by iteratively recombineering synthetic DNA, achieving the highest number of codon substitutions in a single organism.

Nucleic Acids Research · May 2, 2017Peer-reviewedSynthetic Biology