Beth A. Costine

This study examines seizure patterns in a porcine model of post-traumatic epilepsy, finding that seizures start focally and evolve to generalized convulsions with stereotypical behaviors.

This study examines age-dependent changes in NKCC1 and SPAK expression following TBI in piglets, identifying potential therapeutic targets for pediatric TBI.

The paper investigates how brief apnea and hypoventilation (A&H) after seizures in a severe TBI model reduces seizure duration and shifts seizure location for several hours.

This paper develops techniques for high-resolution 2-photon imaging of fluorescent proteins in living swine brains, addressing challenges in motion artifact and large animal imaging.

This paper describes a long-term video EEG monitoring system in a porcine model of post-traumatic epilepsy, demonstrating its utility for studying epileptogenesis over 14 months.