David Y. Chung

This study develops a high-resolution 23Na-MRI platform using implanted RF coils to detect ischemic brain injury with improved contrast-to-noise ratio.

This study examines age-dependent changes in NKCC1 and SPAK expression following TBI in piglets, identifying potential therapeutic targets for pediatric TBI.

This study shows that smooth muscle dysfunction caused by ACTA2 mutations leads to cerebrovascular reserve failure, increasing brain vulnerability to hypoperfusion and injury.

This study introduces a non-invasive method to induce cortical spreading depolarizations in rodents using olfactory bulb pinprick, showing reliable CSD induction without cortical injury.

This paper develops a customized CRISPR-Cas9 base editor to correct the ACTA2 R179H mutation in a mouse model of MSMDS, improving survival and rescuing vascular and neurological phenotypes.

The paper investigates how brief apnea and hypoventilation (A&H) after seizures in a severe TBI model reduces seizure duration and shifts seizure location for several hours.

This study shows that subarachnoid hemorrhage in mice causes early and lasting changes in functional connectivity and cognitive performance.