Puri Fortes

The paper identifies a large class of non-canonical cancer-germline antigens (ncCGAs) from lncRNAs and mRNA untranslated regions, showing their potential as immunotherapeutic targets.

This study identifies ATF4 as a key driver of immune evasion in β-catenin-driven hepatocellular carcinoma by programming a proline-dependent metabolic axis that suppresses anti-tumor immunity.

The paper identifies stop-loss mutations in cancer genomes, showing enrichment in cancer-related genes and potential immunological consequences.

The paper introduces ELATUS, a computational framework for detecting functional lncRNAs from scRNA-seq data, showing improved detection and biological relevance compared to traditional methods.

The paper identifies non-canonical ORFs as a significant source of tumor-specific antigens in liver cancer, showing they can trigger immune responses and are shared among a substantial proportion of patients.