Author

A. A. Pochtovyi

Federal State Budget Institution “National Research Centre for Epidemiology and Microbiology Named after Honorary Academician N. F. Gamaleya” of the Ministry of Health of the Russian Federation, Moscow 123098, RussiaORCID 0000-0003-1107-9351Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Andrei E. SiniaviniD· 2 shared Vladimir A. GushchiniD· 2 shared Alexander L. Gintsburg· 1 shared Anastasia N. Zolotar· 1 shared D. A. ReshetnikoviD· 1 shared Daria D. KustovaiD· 1 shared Denis A. KleymenoviD· 1 shared Denis Y. LogunoviD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersImmunology

Andrei E. SiniavinORCID

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2 papers

Recent·Most cited

ImmunologybioRxivDec 30, 2023

Major role of S-glycoprotein in providing immunogenicity and protective immunity in mRNA lipid nanoparticle vaccines based on SARS-CoV-2 structural proteins

Evgeniia N. Bykonia, Denis A. Kleymenov, Vladimir A. Gushchin…·Alexander L. Gintsburg

This study evaluates mRNA-LNP vaccines encoding SARS-CoV-2 structural proteins, finding that the S protein enhances immune responses to N protein, while M protein has low immunogenicity.

DOI 10.3390/vaccines12040379

mousebulk RNA-seq

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MicrobiologybioRxivPreprintDec 22, 2023

Lethality of West Nile virus strains in a mouse model

A. E. Siniavin, I. V. Dolzhikova, A. A. Pochtovyi…·V. A. Gushchin

This study evaluates the lethality of different West Nile virus strains in a mouse model, highlighting the impact of amino acid substitutions on pathogenesis and vaccine development.

DOI 10.1101/2023.12.22.572994

mouseexperimental assay

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