Camille Boutin

The Joubert syndrome protein CSPP1 is a conserved regulator of vertebrate multiciliogenesis and motile cilia function

This study identifies CSPP1 as a conserved regulator of multiciliogenesis and motile cilia function in vertebrates, showing its role in centriole amplification, basal body migration, and ciliary structure and function.

Robust ciliary flows protect early Xenopus embryos from pathogens independent of multiciliated cell patterning

The paper investigates how ciliary flows in Xenopus embryos protect against pathogens, showing robustness in pathogen clearance despite variations in MCC distribution.

Deciphering the dynamic proteome of multiciliated cells

This study generates a stable MCC line to profile proteome dynamics during differentiation, identifying CDK7 as a critical regulator in Xenopus and human systems.

Loss of Elp3 impairs the maturation tempo of brain ependymal cells

This study shows that loss of Elp3 in mouse forebrain causes microcephaly and hydrocephalus due to impaired ependymal cell maturation and cilia dysfunction.

Lrrcc1 and Ccdc61 are conserved effectors of multiciliated cell function

This study identifies Lrrcc1 and Ccdc61 as essential components of basal bodies in multiciliated cells, showing their role in ciliary function and fluid flow in Xenopus embryos.