Molecular BiologybioRxivPreprint
Selective miniprotein inhibitors of Aurora-A kinase designed using interaction-motif scaffolding
Jennifer A. Miles, Bob Schiffrin, James W. Holder…·Richard W. Bayliss
The paper designs and tests miniprotein inhibitors of Aurora-A kinase using structure-guided protein design, achieving high potency and selectivity over Aurora-B.
DOI 10.64898/2026.07.12.737516