Author

Fanni V. Gergely

University of OxfordORCID 0000-0002-2441-8095Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Sean Anthony BurnapiD· 2 shared Weston B. StruweiD· 2 shared Aaron T. L. LuniD· 1 shared Alexis R. BarriD· 1 shared Bob SchiffriniD· 1 shared Chris BakaliD· 1 shared Duncan T. OdomiD· 1 shared Elisa VitielloiD· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersDevelopmental Biology

Sean Anthony BurnapORCID

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3 papers

Recent·Most cited

Human Choroid Plexus Organoids Progress to Postnatal-like Maturation and Reveal a Closing Window of Developmental Plasticity

Elizabeth Joy Apsley, See Swee Tang, Elisa Vitiello, Ivan Imaz-Rosshandler, Marian Fernández-Otero, Kyriaki Sapidou, Sean Anthony Burnap, Weston B. Struwe, Milos Pjanic, John F. Fullard, Jaroslav M. Bendl, Panos Roussos, Katherine R. Long, Fanni V. Gergely, Madeline A. Lancaster, Laura Pellegrini

This study uses single-cell RNA sequencing to track the maturation of human choroid plexus organoids and identifies a stage-dependent window of developmental plasticity.

bioRxiv · Oct 14, 2026 · PreprintDevelopmental Biology

Selective miniprotein inhibitors of Aurora-A kinase designed using interaction-motif scaffolding

Jennifer A. Miles, Bob Schiffrin, James W. Holder, Emily J. Wallis, Iain W. Manfield, Sean Anthony Burnap, Weston B. Struwe, Fanni V. Gergely, Richard W. Bayliss

The paper designs and tests miniprotein inhibitors of Aurora-A kinase using structure-guided protein design, achieving high potency and selectivity over Aurora-B.

bioRxiv · Jul 13, 2026 · PreprintMolecular Biology

Specificity of RNAi, LNA and CRISPRi as loss-of-function methods in transcriptional analysis

Lovorka Stojic, Aaron T. L. Lun, Jasmin Mangei, Patrice Mascalchi, Valentina Quarantotti, Alexis R. Barr, Chris Bakal, John C. Marioni, Fanni V. Gergely, Duncan T. Odom

This study compares the off-target effects of RNAi, antisense oligonucleotides, and CRISPRi in transcriptomic analyses, showing that all methods have non-negligible off-target effects and recommend using multiple LOF methods for functional validation.

Nucleic Acids Research · May 9, 2018Peer-reviewedGenomics