Author

Sparsh Makhaik

University of Massachusetts AmherstORCID 0000-0001-7622-1502Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Cedric E. BobstiD· 1 shared Chenzhou HaoiD· 1 shared Euna YooiD· 1 shared Jasna FejzoiD· 1 shared Jeanne A. HardyiD· 1 shared Marcin DrągiD· 1 shared Matthew S. BogyoiD· 1 shared Michael WestbergiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Cedric E. BobstORCID

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1 paper

Recent·Most cited

A Robust Fluorogenic Substrate for Chikungunya Virus Protease (nsP2) Activity

Sparsh Makhaik, Wioletta Rut, Shruti Choudhary, Tulsi Upadhyay, Chenzhou Hao, Michael Westberg, Cedric E. Bobst, Euna Yoo, Jasna Fejzo, Michael Z. Lin, Matthew S. Bogyo, Paul R. Thompson, Marcin Drąg, Jeanne A. Hardy

This paper develops a fluorogenic substrate for Chikungunya virus protease (nsP2) that improves signal-to-noise ratio and specificity for inhibitor screening.

Protein Science · Feb 21, 2025Peer-reviewedBiochemistry