Author

Jeanne A. Hardy

University of Massachusetts AmherstORCID 0000-0002-3406-7997Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Cedric E. BobstiD· 1 shared Chenzhou HaoiD· 1 shared Euna YooiD· 1 shared Irina SagarbarriaiD· 1 shared Jasna FejzoiD· 1 shared Jiahui WuiD· 1 shared Jing HeiD· 1 shared Marcin DrągiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

Cedric E. BobstORCID

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2 papers

Recent·Most cited

Orthogonal RNA-regulated destabilization domains for three-color RNA imaging with minimal RNA perturbation

Tien G. Pham, Omoyemi Ajayi, Jing He, Irina Sagarbarria, Jeanne A. Hardy, Jiahui Wu

The paper introduces two orthogonal RNA-regulated destabilization domains for three-color mRNA imaging in mammalian cells with minimal RNA perturbation.

Nature Methods · Dec 17, 2025Peer-reviewedBioengineering

A Robust Fluorogenic Substrate for Chikungunya Virus Protease (nsP2) Activity

Sparsh Makhaik, Wioletta Rut, Shruti Choudhary, Tulsi Upadhyay, Chenzhou Hao, Michael Westberg, Cedric E. Bobst, Euna Yoo, Jasna Fejzo, Michael Z. Lin, Matthew S. Bogyo, Paul R. Thompson, Marcin Drąg, Jeanne A. Hardy

This paper develops a fluorogenic substrate for Chikungunya virus protease (nsP2) that improves signal-to-noise ratio and specificity for inhibitor screening.

Protein Science · Feb 21, 2025Peer-reviewedBiochemistry