Author
Harvard UniversityORCID 0000-0001-7647-3240Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Malvika Tejura, Y P Chen, Abbye E. McEwen…·Lea M. Starita
The paper develops a scalable workflow to reclassify variants of uncertain significance using experimental and predictive evidence, resolving 75% of VUS in 40 genes.
Ross Stewart, Florent Laval, Georges Coppin…·Predrag Radivojac A
MutPred-PPI predicts interaction-specific effects of missense variants using graph attention networks, showing strong performance on both seen and unseen proteins.
Harley O’Connor Mount, Malene L. Urbanus, Dayag Sheykhkarimli…·Alexander W. Ensminger
The paper uses a yeast two-hybrid screen to identify novel effector-effector interactions in L. pneumophila, doubling the known number of such interactions.
Charlotte Vandermeulen, Tina M. O’Grady, Jérôme Wayet…·Jean‐Claude Twizere
This study shows that Tax and HBZ, viral oncoproteins, alter mRNA splicing in T-cells by interacting with spliceosome components, leading to changes in cancer-related genes.
Katja Luck, Dae‐Kyum Kim, Luke Lambourne…·Michael A. Calderwood
The paper presents HuRI, a comprehensive human protein-protein interaction map, and demonstrates its utility in understanding cellular function and disease mechanisms.