Rebecca Anne Simmons

Multi-omic profiling defines subtype-specific extracellular vesicle signatures in early human pregnancy

The paper compares small and large extracellular vesicles from healthy pregnancies to identify subtype-specific cargo differences and establish a reference for normal EV biology.

Perinatal Semaglutide Treatment Improves Maternal Health and Mitigates Offspring Metabolic Dysfunction in a Mouse Model of Maternal Obesity

Exposure to a low dose mixture of endocrine disrupting chemicals alters the brain transcriptome and animal behavior

This study shows that low-dose mixtures of endocrine disrupting chemicals alter brain transcriptomes and behavior in mice, with sex-specific effects and changes in cell-cell signaling.

The effect of intrauterine growth restriction on the developing pancreatic immune system

This study identifies immune cell populations in the developing rat pancreas and spleen, showing IUGR disrupts their composition and is influenced by tissue environment and sex.

Maternal exercise rescues fetal akinesia-impaired joint and bone development

This study shows maternal exercise rescues skeletal defects in fetal akinesia by directly stimulating fetal joint and bone development through mechanical forces.

SPAG7 deletion causes intrauterine growth restriction, resulting in adulthood obesity and metabolic dysfunction

This study identifies SPAG7 gene mutations in mice causing intrauterine growth restriction and adult obesity through reduced energy expenditure and mitochondrial dysfunction.