Quan Wang

This study uses ABEL-FRET to map RNA structural changes during Cas9 RNP assembly, revealing how guide RNA flexibility is modulated through different assembly states.

This study identifies the kinase KEY1 as a regulator of pyrenoid condensate size and dynamics in Chlamydomonas reinhardtii, showing it disrupts phase separation interactions to control condensate dissolution during the cell cycle.

This paper introduces dual-view microscopy to measure single-molecule dipole orientations with improved precision and three-dimensional accuracy.

This study demonstrates electrokinetic detection of single-molecule phosphorylation, resolving phosphorylated sites and monitoring kinase cycles with single turnover resolution.