Lauren Sandeman

This paper develops and validates a novel murine model of in-stent neoatherosclerosis that replicates human disease characteristics.

This study identifies sex-specific mitochondrial dysfunction in endothelial cells of diabetic PAD patients, showing that MitoQ improves vascular function in females.

This study shows that reconstituted high-density lipoproteins (rHDL) restore impaired PDK4/PDC axis activity and angiogenic responses in diabetic endothelial cells under hypoxia.

This paper develops Por-HDL-NPs for atherosclerosis theranostics, showing they reduce inflammation, promote cholesterol efflux, and visualize plaques via imaging.